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The oral semaglutide guide covers the specific protocols, bioavailability differences, and practical considerations of the pill form

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This is higher than the general recommendation for tirzepatide users (1.0 to 1.2 g/kg) because of the additive muscle loss risk from autoimmune disease

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Almost a third of people treated with the higher dose had a bodyweight reduction of more than 25%, and 83.4% of patients with prediabetes at the start of the trial had returned to normal blood sugar levels by the end of the trial, compared to 73.8% for the standard dose and 36.6% for the placebo group